Dr. Jay S. Duker MD

Practice: New England Eye Center

Location: Boston, Massachusetts

Website: https://www.neec.com/

Phone: 617-636-4604

Jay S. Duker, M.D. is an Adjunct Professor of Ophthalmology at the Tufts Medical Center and Tufts University School of Medicine in Boston, Massachusetts. He served as the Chair of the Ophthalmology Department at Tufts between 2001 and 2021.

Through his varied ophthalmology-related activities spanning four decades of practice, he has developed a local, regional, national, and international reputation as a highly successful clinician, surgeon, diagnostician, educator, researcher, administrator, and entrepreneur.

  • Clinical Interests

    Dr. Duker’s part-time clinical practice is limited to medical diseases of the posterior segment of the eye including age-related macular degeneration (AMD), diabetic retinopathy, retinal vascular diseases, posterior segment uveitis, and intraocular tumors. He has a particular interest in rare and unusual retinal disorders, especially those connected to systemic disease.

    Research Interests

    Novel imaging techniques of the eye, especially optical coherence tomography (OCT), drug delivery to the posterior segment, retinal vascular disorders and posterior segment uveitis. Over the past two decades, Dr. Duker has been instrumental in discovering clinical applications of OCT technology.

    Fellowship

    Vitreoretinal Diseases and Surgery and Intraocular Tumors, Wills Eye Hospital

    Residency

    Wills Eye Hospital

    Medical School

    Jefferson Medical College of Thomas Jefferson University

    Academic Appointment

    Adjunct Professor of Ophthalmology, Tufts University School of Medicine

    Board Certification

    • American Board of Ophthalmology

    • Professional Honors and Awards

    • 1992. American Academy of Ophthalmology, Honor Award

    • 2003. American Academy of Ophthalmology, Senior Achievement Award

    • 2010. American Society of Retina Specialists, Honor Award

    • 2013. American Society of Retina Specialists, Senior Honor Award

    • 2015. American Academy of Ophthalmology, Life Achievement Honor Award

    • 2015. Brazilian Society of Retina and Vitreous Honor Award

    • 2019. Viki and Jack Farber Vision Research Award, Wills Eye Hospital

    Personal Interests

    Dr. Duker’s current full time position is Chief Operating Officer (COO) of EyePoint Pharmaceuticals, a publicly traded biotech company that specializes in long term drug delivery to the eye.

    Dr. Duker is the founder of several successful businesses including the fifth busiest independent ophthalmic ambulatory surgery center in the United States, SurgiSite Boston.

    Dr. Duker is a founder of Hemera Biosciences, a clinical-stage biotech company developing treatments of eye disease through complement inhibition using a gene therapy delivery system that was acquired by Janssen in 2020, and the Boston Image Reading Center (BIRC).

    • American Medical Association

    • American Academy of Ophthalmology

    • Massachusetts Society of Eye Physicians and Surgeons

    • Massachusetts Medical Society

    • FRAME Fluorescein Angiography Club

    • International Academy of Sports Vision

    • American Society of Retina Specialists

    • New England Ophthalmology Society

    • Association of University Professors in Ophthalmology

    • Principal Founder and Director, SurgiSite Boston

    • Director and Founder, Hemera Biosciences

    • Director and Chair of the Board, Sesen BioDirector, EyePoint PharmaFounding Editor-in-Chief, International Journal of Retina and Vitreous

    • Editorial Board of OSLI Retina, Retina Cases and Brief Reports, and Investigative Ophthalmology and Visual Sciences

  • Books and chapters:

    • Yanoff M, Duker JS, eds. Ophthalmology. Mosby, London, 4 Editions from 1999-2014.

    • Duker JS, Waheed NK, Goldman DR. Handbook of Retinal OCT. Elsevier, Saunders, 2014.

    • Duker JS, Witkin AJ, eds. Age-Related Macular Degeneration Current Management.

    • Slack Incorporated, NJ, 2015.

    • Laver N V, Sitko K, Duker JS, Farhat NA. Ocular Tumors. In: Linda M. McManus, Richard N. Mitchell, editors. Pathobiology of Human Disease. San Diego: Elsevier; 2014. P. 2179-2200.

    Dr. Duker has over 250 papers published in peer-reviewed journals. His manuscripts have appeared in high impact journals and one of them has been among the top 10 referenced ophthalmology research papers over the past five years. Here are a few recent examples:

    • Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P. The International Vitreomacular Traction Study Group Classification of Vitreomacular Adhesion, Traction, and Macular Hole. Ophthalmology. Dec 2013;120(12):2611-9.

    • Duker JS, Moshfeghi AA. Ocriplasmin: A Medical or Surgical Therapy? Retina. Nov/Dec 2013;33(10):2001-2.

    • Lally DR, Duker JS, Mignano JE, Martin S, Witkin AJ. Regression of Choroidal Metastasis from Breast Carcinoma Treated with Gamma Knife Radiosurgery. JAMA Ophthalmology. October 2014;132(10):1248-1249.

    • Fein JG, Branchini LA, Manjunath V, Regatieri CV, Fujimoto JG, Duker JS. Analysis of Short-Term Change in Subfoveal Choroidal Thickness in Eyes with Age-Related Macular Degeneration using Optical Coherence Tomography. OSLI Retina. Jan/Feb 2014;45(1):32-7.

    • Mehta M, Rasheed RA, Duker JS, Reichel E, Feinberg E, Husain D, Foster CS, Laver NV. Vitreous Evaluation: A Diagnostic Challenge. Ophthalmology. Mar 2015;122(3):531-7.

    • Inoue M, Jung JJ, Balaratnasingam C, Dansingani KK, Dhrami-Gavazi E, Suzuki M, de Carlo TE, Shahlaee A, Klufas MA, El Maftouhi A, Duker JS, Ho AC, Quaranta-El Maftouhi M, Sarraf D, Freund KB, COFT-1 Study Group. A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization. IOVS. July 2016;57:314-23.

FAQ

At the Jack McGovern Coats’ Disease Foundation, we are often contacted by anxious parents or patients who are seeking information after receiving a diagnosis of Coats’ Disease. The questions below are provided as a resource to assist you as you and your doctor decide the best approach for treatment. These questions do not constitute any form of medical advice or diagnosis. Each patient is unique. An experienced retinal specialist who has examined the patient is the best source of information for diagnosis and treatment. We always recommend getting a second opinion.

Questions to Ask Your Doctor (Download PDF)

  • Ahead of any treatments or procedures, it is important to ask yourself and the doctor the following questions:

    • How do you know that this is Coats’ Disease?

    • Has your doctor treated other patients with Coats’ Disease?

    • Have you sought a second opinion? If not, please consult our Doctor Directory for knowledgeable doctors in your area.

    • What Stage of Coats’ Disease is he/she in?

    • Will his/her vision get worse over time?

    • Will the eye have pain?

    • Will his/her eye start to turn out? Is muscle corrective surgery an option?

    • Are cataracts likely?

    • How likely is glaucoma? (due to retinal detachment)

    • Is there calcification?

    • What is the anticipated disease progression?

    • Is there a thorough vision exam available?

    • Where is the vision affected? (central/peripheral/distance)

    • Does he/she have depth perception? (3D visibility)

    • What about the non-Coats’ eye?

    • To what extent is his/her vision affected?

    • Will we be able to use this as a baseline to measure progress/decline?

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